When Should You Introduce Enzymes Into Your Supplement Routine?
In the world of wellness and functional medicine, it’s easy to get lost in the noise of vitamins, minerals, adaptogens, and probiotics. But there’s one category of supplement that’s often overlooked, even though it plays a critical role in digestion, absorption, and overall vitality: enzymes.
Whether you’re already supplementing or just starting out, understanding when and why to bring enzymes into your routine could be the missing piece to unlocking better energy, improved gut health, and a properly nourished body.
In this blog, we unpack:
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What enzymes are and what they do
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Common signs your body may be enzyme-deficient
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The root causes of enzyme depletion
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Who needs to supplement and when
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How enzymes work alongside FLORISH and FULFIXER
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How to choose the right enzyme blend for your needs
What Are Enzymes and Why Are They So Important?
Enzymes are protein-based catalysts—special molecules that help your body break down food and convert it into usable nutrients. They’re involved in nearly every function in the body, especially digestion.
There are three main types of digestive enzymes:
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Proteases – break down proteins
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Lipases – break down fats
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Amylases – break down carbohydrates
Without these enzymes, your body struggles to absorb nutrients even from the cleanest, healthiest food.
In functional medicine, we also recognise the importance of systemic enzymes, which work beyond digestion to:
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Reduce inflammation
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Break down scar tissue
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Support immune modulation
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Clear toxins and metabolic waste
But for most people, the first signs of enzyme depletion show up in the gut.
7 Signs You Might Need Enzyme Support
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Bloating After Meals
Especially if you feel distended shortly after eating—your body may not be breaking down food efficiently. -
Undigested Food in Stool
A clear sign that your digestive system isn’t completing the process. -
Fatigue After Eating
If meals make you tired instead of energised, you might not be extracting nutrients properly. -
Frequent Gas or Belching
These are classic symptoms of incomplete digestion and fermentation in the gut. -
Greasy or Floating Stools
This could signal a lipase deficiency, where fats aren’t being broken down properly. -
Food Sensitivities or Intolerances
Especially if they appear later in life—your gut may be underperforming and reacting to partially digested proteins. -
Low B12, Iron, or Amino Acids
Blood tests showing nutritional deficiencies despite a good diet point to absorption issues, often rooted in enzyme insufficiency.
What Causes Enzyme Deficiency?
There are several causes of low digestive enzyme output—some lifestyle-based, others more clinical:
🔹 Ageing
As we age, the body produces fewer digestive enzymes. By the time we reach 40 or 50, many of us already have diminished enzyme capacity—especially if we’ve had a history of gut problems.
🔹 Processed Diets
Cooked and processed foods contain virtually no living enzymes. A lifetime of eating “dead” food puts extra pressure on your pancreas to produce everything itself.
🔹 Gut Damage
If you’ve had IBS, leaky gut, SIBO, candida, or food poisoning, the lining of your gut may be inflamed and your enzyme production compromised.
🔹 Chronic Stress
Stress reduces stomach acid and digestive secretions—including enzymes.
🔹 Acid Blockers or Antacids
These drugs interfere with the natural acidity required to trigger enzyme release, impairing digestion further.
🔹 Microbiome Imbalance
An unhealthy gut microbiome can't support enzyme production. This is where spore-based probiotics like FLORISH come in—by restoring balance and giving your gut the resilience to reboot natural enzyme output.
So When Should You Start Supplementing with Enzymes?
Here’s a guide to when enzyme supplementation becomes essential:
✅ 1. You Experience Digestive Discomfort After Eating
Especially if it's consistent across many food groups—not just dairy or gluten.
✅ 2. You’ve Had a Long History of Gut Issues
If you’ve tried probiotics, elimination diets, and supplements with limited results, enzymes could be the missing key.
✅ 3. You’re Starting a New Supplement Regime
Especially with potent blends like FLORISH (Spore Probiotics with Fulvic Acid) or FULFIXER (Fulvic Acid capsules)—digestive enzymes can help your body better absorb the powerful actives.
✅ 4. You’re Recovering from Antibiotics or GI Infections
These disrupt enzyme production in the gut. Enzymes help rebuild function.
✅ 5. You’ve Been Diagnosed with Conditions Like Pancreatitis, Celiac, or Crohn’s
These conditions blunt enzyme release and require medical-grade enzyme support.
✅ 6. You’re Over 40 and Struggling with Energy or Nutrition
Even without gut symptoms, ageing alone reduces enzyme output—starting low-dose enzyme support can significantly improve vitality.
How Enzymes Work with FLORISH and FULFIXER
At Sebastian Siebert Supplements, our formulations are designed to work together holistically. Here’s how enzymes slot into your existing supplement protocol:
🦠 FLORISH + Enzymes
Spore probiotics rebalance the gut and reseed beneficial bacteria, while enzymes support the immediate breakdown of foods and reduce the toxic load. Together, they:
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Improve digestion and nutrient extraction
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Minimise bloating and inflammation
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Assist in microbial detox
⚡ FULFIXER + Enzymes
Fulvic acid enhances cellular uptake of nutrients and chelates toxins—but this process starts at the gut wall. Enzymes prepare nutrients for fulvic acid to do its job more efficiently, helping:
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Enhance mineral uptake
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Improve cellular hydration
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Detoxify the gut lining gently
Choosing the Right Enzyme Supplement
Not all enzyme blends are created equal. Here’s what to look for:
✔️ Broad Spectrum
Look for blends that include protease, amylase, lipase and lactase, cellulase, and bromelain for full-spectrum action.
✔️ Stability in Stomach Acid
Some enzyme supplements get destroyed in the stomach. Choose acid-stable enzymes or enteric-coated options.
✔️ Plant-Based or Microbial Source
These tend to be better tolerated, especially for long-term use and in vegan/vegetarian diets.
✔️ No Fillers or Additives
Just like with any supplement, avoid anything with titanium dioxide, synthetic colours, or bulking agents.
How to Take Enzymes for Best Results
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With meals: Take enzymes just before or with your first bite of food to help with digestion.
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On an empty stomach: Some systemic enzyme blends (like serrapeptase or nattokinase) are taken between meals for inflammation or clot support.
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Stay hydrated: Enzymes work best in a well-hydrated gut—pair with clean, mineral-rich water, especially when using FLORISH and FULFIXER.
Conclusion: Enzymes Are Essential When Digestion Is Failing You
Modern living, processed foods, stress, and medication use have all conspired to reduce our body’s natural enzyme output. While a good probiotic and fulvic acid regimen lays the foundation for health, enzymes complete the puzzle, ensuring everything you eat and supplement with is being used by the body.
Introducing enzymes isn’t a luxury—it’s often a necessity, especially if you’re over 40, recovering from gut issues, or feeling like you’re just not getting the benefits you should from your supplements or your food.
At Sebastian Siebert Supplements, we believe in layered, synergistic support. Enzymes, when introduced at the right time, can transform your gut health, your energy, and your resilience—from the inside out.